Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 5/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971142 | 0.86 | SYK (0.41) | SYK | |
| SCHEMBL27388202 | 0.84 | PKMYT1 (0.46) | PKMYT1KDM4EWEE1SYKCDK1 | |
| SCHEMBL27388203 | 0.83 | PKMYT1 (0.39) | PKMYT1L3MBTL1KDM4EWEE1TGFBR1 | |
| SCHEMBL27388208 | 0.83 | PKMYT1 (0.37) | PKMYT1L3MBTL1KDM4EWEE1GRK6 | |
| SCHEMBL27388206 | 0.80 | PKMYT1 (0.39) | PKMYT1L3MBTL1KDM4EWEE1CDK1 | |
| SCHEMBL27388207 | 0.79 | TGFBR1 (0.35) | PKMYT1L3MBTL1KDM4EWEE1TGFBR1 | |
| SCHEMBL27388205 | 0.78 | PKMYT1 (0.36) | PKMYT1L3MBTL1WEE1TGFBR1SYK | |
| SCHEMBL30971209 | 0.74 | SYK (0.48) | PKMYT1SYKJAK2MAP4K4RPS6KA3 | |
| SCHEMBL30905525 | 0.72 | PKMYT1 (0.43) | PKMYT1L3MBTL1KDM4EWEE1CDC7 | |
| SCHEMBL27397956 | 0.72 | PKMYT1 (0.43) | PKMYT1L3MBTL1KDM4EWEE1CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |