Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27710784 | 0.98 | TPMT (0.40) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL27951871 | 0.84 | TPMT (0.44) | MAPTMEN1ALDH1A1KMT2ATPMT | |
| SCHEMBL7544521 | 0.82 | RARB (0.42) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL27388069 | 0.82 | RARB (0.42) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL3293447 | 0.81 | RARB (0.62) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL31213311 | 0.81 | RARB (0.62) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL17060014 | 0.81 | RARB (0.62) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL9096952 | 0.81 | RARB (0.41) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL31213309 | 0.81 | RARB (0.62) | RARBMAPTMEN1ALDH1A1RARA | |
| SCHEMBL28032028 | 0.81 | RARB (0.62) | RARBMAPTMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094126-C | Pyrroloazepine compounds | SUNTORY LTD (JP) | 2002-11-13 | — | — | CN | disclosed |
| CN-1219173-A | Pyrroloazepine compounds | SUNTORY LTD (JP) | 1999-06-09 | — | — | CN | disclosed |