Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389337 | 0.98 | RARB (0.41) | TPMTRARBMEN1KMT2AALDH1A1 | |
| SCHEMBL27951871 | 0.85 | TPMT (0.44) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27485851 | 0.81 | CYP4A11 (0.46) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL16749638 | 0.80 | CA12 (0.48) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27388069 | 0.80 | RARB (0.42) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8413501 | 0.80 | RARB (0.61) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL7544521 | 0.80 | RARB (0.42) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL6139365 | 0.80 | RARB (0.61) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL27829550 | 0.79 | CYP4A11 (0.44) | TPMTRARBALDH1A1MAPTCA12 | |
| SCHEMBL9096952 | 0.78 | RARB (0.41) | RARBMEN1KMT2AALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402032-C | Tetrahydroquinoline analogs as muscarinic agonists | ACADIA PHARM INC (US) | 2008-07-16 | — | — | CN | disclosed |