Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.68 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739073 | 0.91 | DRD3 (0.73) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2739071 | 0.90 | DRD3 (0.77) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2739074 | 0.89 | DRD3 (0.67) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL218256 | 0.87 | DRD3 (0.72) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2739075 | 0.85 | DRD3 (0.64) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2738823 | 0.84 | KDM4E (0.70) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7824014 | 0.84 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10738656 | 0.84 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL29351730 | 0.84 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL34292 | 0.84 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |