Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392163 | 0.87 | BRD4 (0.52) | CHEK2BRD4GPR119CSF1RHDAC1 | |
| SCHEMBL27392241 | 0.72 | BRD4 (0.48) | BRD4TDP1 | |
| SCHEMBL1376617 | 0.71 | GPR119 (0.59) | CHEK2GPR119HDAC1HPGDKDM4E | |
| SCHEMBL18842715 | 0.71 | GPR119 (0.57) | CHEK2GPR119HDAC1KMT2A | |
| SCHEMBL15539074 | 0.71 | GPR119 (0.57) | CHEK2GPR119HDAC1 | |
| SCHEMBL27393961 | 0.70 | CSF1R (0.51) | CHEK2GPR119CSF1RHDAC1KDM4E | |
| SCHEMBL27392162 | 0.70 | GPR119 (0.53) | CHEK2BRD4GPR119CSF1RHDAC1 | |
| SCHEMBL15412759 | 0.69 | GPR119 (0.58) | CHEK2GPR119HDAC1KDM4EALDH1A1 | |
| SCHEMBL12834985 | 0.69 | GPR119 (0.58) | CHEK2GPR119CSF1RHDAC1KDM4E | |
| SCHEMBL30812315 | 0.69 | BRD4 (0.58) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054955-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |