Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519658 | 0.84 | EPHX2 (0.43) | EPHX2EPHX1GAACYP1A2TDP1 | |
| SCHEMBL748985 | 0.83 | GAA (0.58) | GAACYP1A2TDP1SMN1; SMN2KDM4E | |
| SCHEMBL4537101 | 0.81 | NOS2 (0.50) | NOS2GAATDP1SMN1; SMN2KDM4E | |
| SCHEMBL12036169 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1GAACYP1A2TDP1 | |
| SCHEMBL13673383 | 0.79 | NOS2 (0.48) | NOS2EPHX2GAASMN1; SMN2 | |
| SCHEMBL27282774 | 0.79 | NOS2 (0.43) | NOS2GAASMN1; SMN2 | |
| SCHEMBL748984 | 0.78 | CYP1A2 (0.44) | EPHX2EPHX1CYP1A2TDP1SMN1; SMN2 | |
| SCHEMBL190928 | 0.78 | CYP1A2 (0.48) | EPHX2EPHX1CYP1A2TDP1SMN1; SMN2 | |
| SCHEMBL28956103 | 0.76 | EPHX2 (0.40) | EPHX2EPHX1GAACYP1A2TDP1 | |
| SCHEMBL28956102 | 0.76 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |