Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262500 | 0.94 | FFAR1 (0.63) | HDAC2HDAC1FFAR1MGLLMMP12 | |
| SCHEMBL5801662 | 0.89 | FFAR1 (0.71) | HDAC2HDAC1FFAR1MMP12ABCC4 | |
| SCHEMBL1285919 | 0.88 | MAPT (0.70) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL1958621 | 0.87 | FFAR1 (0.75) | HDAC2HDAC1FFAR1MGLLMAPT | |
| SCHEMBL1327206 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL1285525 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL2627816 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL1404165 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL21359026 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA | |
| SCHEMBL5981360 | 0.86 | MAPT (0.74) | HDAC2HDAC1MAPTRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085661-C | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1161033-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 1997-10-01 | — | — | CN | disclosed |