Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27396759 | 0.94 | HDAC2 (0.68) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| SCHEMBL5801662 | 0.90 | FFAR1 (0.71) | FFAR1HDAC2HDAC1MMP12ABCC4 | |
| SCHEMBL5020709 | 0.88 | HDAC1 (0.67) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| SCHEMBL7859 | 0.88 | HDAC1 (0.72) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| SCHEMBL1651413 | 0.86 | FFAR1 (0.78) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL23062929 | 0.86 | HDAC1 (0.69) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL30882401 | 0.86 | HDAC1 (0.69) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL30882658 | 0.86 | HDAC1 (0.69) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| Water SCHEMBL28210512 | 0.86 | HDAC1 (0.69) | FFAR1HDAC2HDAC1HDAC3HDAC8 | |
| Biphenyl SCHEMBL27839781 | 0.83 | LTB4R (0.53) | FFAR1HDAC2HDAC1HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347373-A | Derivatives of 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole | TURCONI FRANCO | 1982-08-31 | — | — | US | claimed |
| US-4055664-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESIC | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-10-25 | — | — | US | disclosed |