Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204729 | 0.76 | POLB (0.37) | IDO1PDE9APDE1CHRH4HRH3 | |
| SCHEMBL15893916 | 0.73 | ALDH1A1 (0.33) | CYP1A2CYP3A4CYP2C19PDE1C | |
| SCHEMBL22751285 | 0.73 | HRH3 (0.33) | IDO1PDE9APDE1CHRH3 | |
| SCHEMBL15893923 | 0.72 | TSHR (0.38) | GSK3BADORA2A | |
| SCHEMBL21325275 | 0.71 | BRS3 (0.36) | IDO1DGAT1PDE9APDE1CHRH3 | |
| SCHEMBL20201744 | 0.69 | PDE9A (0.39) | PDE9APDE1CHRH4 | |
| SCHEMBL8542770 | 0.69 | BRS3 (0.43) | IDO1DGAT1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL5655787 | 0.68 | BRS3 (0.37) | IDO1HRH4HRH3 | |
| SCHEMBL24228552 | 0.67 | HRH3 (0.44) | HRH4HRH3 | |
| SCHEMBL21325361 | 0.67 | PDE9A (0.35) | ADORA2APDE9APDE1CHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079223-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1993-12-08 | — | — | CN | disclosed |