Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.49 |
| ▸ | MC3R | P41968 | 7/20 | 0.49 |
| ▸ | MC5R | P33032 | 5/20 | 0.47 |
| ▸ | MC1R | Q01726 | 4/20 | 0.47 |
| ▸ | PRCP | P42785 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576722 | 0.88 | MC4R (0.61) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4576726 | 0.88 | MC4R (0.61) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4591032 | 0.83 | MC4R (0.69) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4577568 | 0.75 | MC4R (0.71) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4592236 | 0.75 | MC4R (0.71) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4591012 | 0.75 | MC4R (0.71) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4576906 | 0.75 | MC4R (0.71) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4576683 | 0.75 | MC4R (0.65) | MC4RMC3RMC5RPRCP | |
| SCHEMBL4576912 | 0.75 | MC4R (0.71) | MC4RMC3RMC5RPRCP | |
| SCHEMBL21035850 | 0.73 | MC4R (0.67) | MC4RMC3RMC5RMC1RPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |