Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.61 |
| ▸ | MC3R | P41968 | 2/20 | 0.61 |
| ▸ | PRCP | P42785 | 11/20 | 0.59 |
| ▸ | MC5R | P33032 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576722 | 1.00 | MC4R (0.61) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4591032 | 0.94 | MC4R (0.69) | MC4RMC3RPRCPMC5R | |
| SCHEMBL27397690 | 0.88 | MC4R (0.49) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4591012 | 0.86 | MC4R (0.71) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4577568 | 0.86 | MC4R (0.71) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4592236 | 0.86 | MC4R (0.71) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4576906 | 0.86 | MC4R (0.71) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4576912 | 0.86 | MC4R (0.71) | MC4RMC3RPRCPMC5R | |
| SCHEMBL27392877 | 0.83 | MC4R (0.73) | MC4RMC3RPRCPMC5R | |
| SCHEMBL4955655 | 0.82 | MC4R (0.73) | MC4RMC3RPRCPMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534074-A4 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1534074-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | Merck & Co., Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004009015-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO., INC. (US) | 2004-01-29 | — | — | WO | claimed |
| EP-1534074-A4 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1534074-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | Merck & Co., Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004009015-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO., INC. (US) | 2004-01-29 | — | — | WO | disclosed |