Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373108 | 0.84 | ADORA2B (0.40) | KDM5BADORA2BKDM4EMEN1NPC1 | |
| SCHEMBL27372069 | 0.67 | ADORA2B (0.39) | KDM5BADORA2BKDM4EMEN1NPC1 | |
| SCHEMBL23505916 | 0.66 | SMN1; SMN2 (0.36) | KDM5BADORA2BKDM4EMEN1NPC1 | |
| SCHEMBL8677229 | 0.65 | KDM5B (0.37) | KDM5B | |
| SCHEMBL8960197 | 0.64 | MAPK11 (0.40) | KDM5BGLALMNA | |
| SCHEMBL16975084 | 0.64 | SMN1; SMN2 (0.69) | KDM4EMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL31462150 | 0.61 | SMN1; SMN2 (0.55) | KDM4ENPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL9378705 | 0.61 | SMN1; SMN2 (0.55) | KDM4ENPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL16975038 | 0.60 | SMN1; SMN2 (0.52) | ADORA2BKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL28531665 | 0.60 | ADORA2B (0.44) | ADORA2BKDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084165-A | 2-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-03-23 | — | — | CN | disclosed |