Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.58 |
| ▸ | PARP6 | Q2NL67 | 4/20 | 0.58 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.58 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25702722 | 0.86 | PARP1 (0.53) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL25693065 | 0.85 | HDAC3 (0.57) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL18135103 | 0.84 | NPC1 (0.56) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26613680 | 0.82 | PARP1 (0.49) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL24724935 | 0.81 | MAPT (0.48) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL30496033 | 0.81 | PARP1 (0.51) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL22912811 | 0.81 | HDAC2 (0.55) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL25361878 | 0.81 | PARP1 (0.51) | PARP1PARP2PARP6PARP3TIPARP | |
| Hydrochloric Acid SCHEMBL25282631 | 0.80 | HDAC2 (0.54) | PARP1PARP2PARP6PARP3TIPARP | |
| Hydrochloric Acid SCHEMBL25375858 | 0.80 | HDAC2 (0.54) | PARP1PARP2PARP6PARP3TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |