Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 12/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.45 |
| ▸ | PARP6 | Q2NL67 | 4/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933096 | 0.88 | PARP1 (0.43) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL27397948 | 0.81 | PARP1 (0.58) | MAPTSMN1; SMN2NPC1RAB9APARP1 | |
| SCHEMBL24932854 | 0.80 | HRH3 (0.46) | PARP1 | |
| SCHEMBL25990173 | 0.76 | HDAC3 (0.44) | SMN1; SMN2KDM4ERAD52MEN1KMT2A | |
| SCHEMBL10256408 | 0.76 | GAA (0.50) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25600497 | 0.75 | HRH3 (0.45) | KDM4E | |
| SCHEMBL5254754 | 0.75 | ALDH1A1 (0.58) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25630786 | 0.74 | HRH3 (0.46) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25721557 | 0.74 | PARP1 (0.58) | MAPTSMN1; SMN2NPC1RAB9APARP1 | |
| SCHEMBL6889419 | 0.73 | GAA (0.54) | MAPTSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |