Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.64 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928079 | 0.96 | CRBN (0.61) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL30602900 | 0.90 | CRBN (0.65) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL24481028 | 0.90 | CRBN (0.65) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL21983035 | 0.90 | CRBN (0.70) | CRBNARDDB1ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL29096741 | 0.89 | CRBN (0.69) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL29927782 | 0.89 | CRBN (0.69) | CRBNARDDB1ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL29710529 | 0.89 | CRBN (0.69) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL29132305 | 0.89 | CRBN (0.69) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL30984742 | 0.89 | CRBN (0.61) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL30984889 | 0.88 | CRBN (0.70) | CRBNARDDB1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123819-A2 | SMALL MOLECULE DEGRADERS OF C-SRC KINASE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-13 | — | — | WO | disclosed |