Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.56 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984709 | 0.95 | CRBN (0.59) | CRBNDDB1ARBTKALK | |
| SCHEMBL30984978 | 0.91 | CRBN (0.62) | CRBNDDB1ARBTKCDK9 | |
| SCHEMBL29986989 | 0.90 | CRBN (0.66) | CRBNDDB1ARBTKCDK9 | |
| SCHEMBL24299348 | 0.90 | CRBN (0.66) | CRBNDDB1ARBTKCDK9 | |
| SCHEMBL30984808 | 0.89 | CRBN (0.59) | CRBNDDB1ARALKCDK9 | |
| SCHEMBL27397986 | 0.89 | CRBN (0.64) | CRBNDDB1ARBTKALK | |
| SCHEMBL30984987 | 0.87 | CRBN (0.64) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL30400867 | 0.86 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL25172415 | 0.86 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29928079 | 0.85 | CRBN (0.61) | CRBNDDB1ARBTKALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |