Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.46 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.42 |
| ▸ | WEE1 | P30291 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.40 |
| ▸ | TEC | P42680 | 3/20 | 0.40 |
| ▸ | BMX | P51813 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905514 | 1.00 | BTK (0.46) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27398539 | 0.88 | CDK2 (0.39) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27398542 | 0.87 | BTK (0.47) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27397964 | 0.86 | BTK (0.42) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27399595 | 0.86 | BTK (0.41) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27398541 | 0.85 | BTK (0.49) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL27398143 | 0.83 | BTK (0.48) | BTKPKMYT1WEE1TECBMX | |
| SCHEMBL27400650 | 0.80 | PARP1 (0.43) | BTKPKMYT1CDK2ITKLCK | |
| SCHEMBL27397958 | 0.79 | BTK (0.43) | BTKPKMYT1WEE1MAP4K1TEC | |
| SCHEMBL30905592 | 0.78 | WEE1 (0.48) | BTKPKMYT1WEE1MAP4K1TEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |