Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | TEC | P42680 | 3/20 | 0.35 |
| ▸ | BMX | P51813 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | LYN | P07948 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | FRK | P42685 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397992 | 0.86 | BTK (0.46) | BTKTECBMXSRCITK | |
| SCHEMBL30905514 | 0.86 | BTK (0.46) | BTKTECBMXSRCITK | |
| SCHEMBL27399023 | 0.81 | BTK (0.39) | BTKTECSRCITKPIM1 | |
| SCHEMBL27400650 | 0.76 | PARP1 (0.43) | BTKJAK3ITKLCKFRK | |
| SCHEMBL27398539 | 0.76 | CDK2 (0.39) | BTKTECBMXSRCITK | |
| SCHEMBL27398143 | 0.74 | BTK (0.48) | BTKJAK3TECBMXSRC | |
| SCHEMBL27398542 | 0.73 | BTK (0.47) | BTKTECBMXSRCITK | |
| SCHEMBL27397994 | 0.72 | PKMYT1 (0.53) | SRCLYNLCKHCKFGR | |
| SCHEMBL30905518 | 0.72 | PKMYT1 (0.53) | SRCLYNLCKHCKFGR | |
| SCHEMBL27398835 | 0.71 | BTK (0.39) | BTKTECSRCITKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |