Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 13/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051251 | 1.00 | TGFBR1 (0.49) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL1830448 | 0.79 | DYRK1A (0.71) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL15639144 | 0.78 | TGFBR1 (0.60) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL31051253 | 0.75 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL19806337 | 0.72 | TGFBR1 (0.51) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL1355263 | 0.72 | DYRK1A (0.53) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL18042075 | 0.70 | TGFBR1 (0.71) | TGFBR1DYRK1AAKT1PIK3CAMTOR | |
| SCHEMBL15638836 | 0.70 | TGFBR1 (0.58) | TGFBR1DYRK1AADORA2AADORA2BADORA1 | |
| SCHEMBL30117545 | 0.70 | TGFBR1 (0.58) | TGFBR1DYRK1AADORA2AADORA2BADORA1 | |
| SCHEMBL19806637 | 0.70 | TGFBR1 (0.52) | TGFBR1DYRK1AAKT1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |