Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.31 |
| ▸ | CENPE | Q02224 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850622 | 0.75 | GRIA2 (0.44) | PKMPKLRMAPK14PTGS1RXFP1 | |
| SCHEMBL7852329 | 0.72 | TP53 (0.41) | PKMTSHRHTTMAPTCENPE | |
| SCHEMBL7850615 | 0.68 | GRIA2 (0.44) | PKMPKLRMAPK14PTGS1NEK1 | |
| SCHEMBL7849856 | 0.67 | TACR1 (0.66) | TSHRHTTMAPTRXFP1 | |
| SCHEMBL7843050 | 0.62 | SLC11A2 (0.43) | PKMHTTSLC11A2 | |
| SCHEMBL13641556 | 0.60 | ADORA1 (0.41) | PKMHTT | |
| SCHEMBL7852458 | 0.59 | TSHR (0.49) | TSHRHTTMAPTSLC11A2 | |
| SCHEMBL17290337 | 0.59 | SLC11A2 (0.55) | MAPK14HTTMAPTSLC11A2 | |
| SCHEMBL2553123 | 0.58 | GPR3 (0.50) | HTTMAPTRXFP1 | |
| SCHEMBL19661324 | 0.58 | TSHR (0.36) | TSHRMAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052004-C | Heterocyclic compounds, their production and use | TALCEDA CHEMICAL IND LTD (JP) | 2000-05-03 | — | — | CN | disclosed |
| CN-1107476-A | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | CN | disclosed |