Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30835912 | 0.91 | CYP1A1 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A1 | |
| SCHEMBL27401904 | 0.80 | HTR2A (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A1 | |
| SCHEMBL22462801 | 0.78 | NFE2L2 (0.45) | CHRNB2CHRNA4HTR2AHTR2CHTR2B | |
| SCHEMBL27401595 | 0.76 | MAOB (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL21723029 | 0.75 | CYP1A1 (0.42) | CYP1A1CYP1B1PDE2ABACE1 | |
| SCHEMBL22462807 | 0.75 | CYP1A1 (0.42) | CYP1A1CYP1B1PDE2ABACE1 | |
| SCHEMBL27401521 | 0.74 | MAOB (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2A | |
| Trifluoroacetic Acid SCHEMBL30836072 | 0.73 | CYP1A1 (0.45) | CYP1A1CYP1B1HTR2AKDM4ESLC6A4 | |
| SCHEMBL27400930 | 0.72 | TEAD1 (0.45) | CYP1A1CYP1B1 | |
| SCHEMBL13841271 | 0.72 | CYP1A1 (0.45) | CYP1A1CYP1B1PDE2AKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |