SCHEMBL27399306

SCHEMBL27399306

CN(C)/C=N/C(=O)c1ccc2ncc(Br)n2c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
HPGD P15428 3/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTT P42858 2/20 0.34
POLB P06746 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GAA P10253 1/20 0.33
ADORA2A P29274 1/20 0.32
TGFBR1 P36897 2/20 0.32
RECQL P46063 1/20 0.32
SCN10A Q9Y5Y9 1/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27399250 0.80 IRAK4 (0.33) ALDH1A1HPGDADORA2ATGFBR1SCN10A
SCHEMBL19950919 0.78 IRAK4 (0.45) ALDH1A1SMN1; SMN2HPGDKMT2AHSD17B10
SCHEMBL31051303 0.78 LMNA (0.52) ALDH1A1SMN1; SMN2HPGDNPSR1MEN1
SCHEMBL31051183 0.78 CYP1A2 (0.35) ALDH1A1SMN1; SMN2HPGDNPSR1MEN1
SCHEMBL27399009 0.78 CYP1A2 (0.35) ALDH1A1SMN1; SMN2HPGDNPSR1MEN1
SCHEMBL27399413 0.76 RIPK2 (0.39) ALDH1A1HPGDGAAADORA2ATGFBR1
SCHEMBL19950854 0.74 KDM4E (0.49) ALDH1A1HPGDHSD17B10POLBTGFBR1
SCHEMBL29229590 0.73 KDM4E (0.36) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL27399244 0.73 IRAK4 (0.42) SMN1; SMN2TGFBR1SCN10AKDM4E
SCHEMBL19950862 0.72 ATM (0.44) ALDH1A1SMN1; SMN2HPGDHTTTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634178-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-22 EP disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed