Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | TEAD1 | P28347 | 10/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | LIPC | P11150 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399389 | 1.00 | LIPG (0.49) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398796 | 1.00 | LIPG (0.49) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398302 | 1.00 | LIPG (0.49) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398290 | 0.89 | LIPG (0.52) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398377 | 0.89 | TEAD1 (0.50) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27400014 | 0.89 | LIPG (0.52) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398294 | 0.89 | LIPG (0.49) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL21958136 | 0.87 | TEAD1 (0.63) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398364 | 0.87 | TEAD1 (0.63) | LIPGCARM1PRMT6TEAD1MMP2 | |
| SCHEMBL27398676 | 0.87 | LIPG (0.46) | LIPGCARM1PRMT6TEAD1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091511-A1 | HETEROCYCLIC TEAD INHIBITORS | LIGHT HORSE THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |