Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633543 | 0.85 | PTGDR2 (0.40) | METAP1PI4KBLCKCYP17A1CA1 | |
| SCHEMBL1066439 | 0.85 | METAP1 (0.45) | METAP1PI4KBLCKCYP17A1CA1 | |
| SCHEMBL13136708 | 0.80 | SMN1; SMN2 (0.43) | MEN1GAAKMT2A | |
| SCHEMBL3039310 | 0.79 | MAPT (0.49) | METAP1PI4KBLCKCYP17A1CA1 | |
| SCHEMBL23960291 | 0.78 | ATR (0.43) | METAP1LCKCYP17A1CA1CA2 | |
| SCHEMBL22774998 | 0.78 | CA1 (0.42) | METAP1LCKCYP17A1CA1CA2 | |
| SCHEMBL1483110 | 0.78 | CA1 (0.42) | METAP1LCKCYP17A1CA1CA2 | |
| SCHEMBL1482420 | 0.76 | LCK (0.47) | METAP1LCKCYP17A1NAMPT | |
| SCHEMBL5029628 | 0.76 | PTPN1 (0.56) | METAP1LCKCYP17A1CA1CA2 | |
| SCHEMBL646870 | 0.76 | ALDH1A1 (0.50) | METAP1CA1RXFP1BRD9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |