Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 8/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835885 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL30835834 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL30836049 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL27399679 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL27399676 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL27399675 | 1.00 | TEAD1 (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL27399822 | 0.93 | MAOB (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL27399824 | 0.93 | MAOB (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL31556553 | 0.93 | MAOB (0.57) | TEAD1MAOBMAOADCUN1D1LMNA | |
| SCHEMBL30836081 | 0.91 | TEAD1 (0.54) | TEAD1MAOBMAOADCUN1D1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |