Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | Q9HBH1 | 7/20 | 0.32 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57601 | 0.91 | TUBB1 (0.61) | TUBB1DPP4PDF | |
| SCHEMBL27400350 | 0.86 | TUBB1 (0.63) | TUBB1PDF | |
| SCHEMBL26606758 | 0.85 | TUBB1 (0.51) | TUBB1PDF | |
| SCHEMBL20732247 | 0.84 | TUBB1 (0.59) | TUBB1DPP4PDF | |
| SCHEMBL26606614 | 0.83 | DPP4 (0.49) | TUBB1DPP4 | |
| SCHEMBL12202102 | 0.82 | TUBB1 (0.45) | TUBB1 | |
| SCHEMBL15429788 | 0.81 | TUBB1 (0.41) | TUBB1PDF | |
| SCHEMBL16169533 | 0.81 | TUBB1 (0.41) | TUBB1PDF | |
| SCHEMBL58470 | 0.81 | TUBB1 (0.41) | TUBB1PDF | |
| SCHEMBL24409879 | 0.81 | TUBB1 (0.54) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | FCGRT, QARS1, INHA | TUBB1 436/4885DPP4 3881/4885PDF 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.