Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302855 | 0.91 | — | — | |
| SCHEMBL28201803 | 0.91 | PTGS1 (0.40) | LMNAPTGS1AKR1C3FFAR3LCK | |
| SCHEMBL34404 | 0.91 | — | — | |
| SCHEMBL149416 | 0.91 | — | — | |
| SCHEMBL8935075 | 0.88 | — | — | |
| Maleic Acid SCHEMBL4606400 | 0.80 | TSHR (0.50) | LMNAALOX15PTGS1AKR1C3FFAR3 | |
| Methacrylic Acid SCHEMBL7518017 | 0.80 | TDP1 (0.36) | PTGS1AKR1C3FFAR3LCKFYN | |
| Phosphoric Acid SCHEMBL15157054 | 0.80 | PTGS1 (0.34) | PTGS1AKR1C3FFAR3LCKFYN | |
| Methacrylic Acid SCHEMBL27617320 | 0.80 | TDP1 (0.36) | PTGS1AKR1C3FFAR3LCKFYN | |
| Fumaric Acid SCHEMBL4606405 | 0.80 | TSHR (0.50) | LMNAALOX15PTGS1AKR1C3FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108647-A | Thiol-terminated hydroxyamides | ROHM & HAAS (US) | 1995-09-20 | — | — | CN | disclosed |
| CN-1105022-A | Thiol-terminated hydroxyamides | ROHM & HAAS (US) | 1995-07-12 | — | — | CN | disclosed |
| CN-1028526-C | Process for preparing mercapto-terminated hydroxyamides | ROHM & HAAS (US) | 1995-05-24 | — | — | CN | disclosed |
| CN-1049496-A | THIOL-TERMINATED HYDROXYAMIDES | ROHM & HAAS (US) | 1991-02-27 | — | — | CN | disclosed |