Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27933722 | 0.95 | TSHR (0.36) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Acetic Acid SCHEMBL663243 | 0.92 | CYP2C19 (0.40) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| SCHEMBL28022926 | 0.91 | CYP3A4 (0.39) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Benzene SCHEMBL19838142 | 0.91 | TSHR (0.41) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Benzene SCHEMBL27434033 | 0.91 | TSHR (0.41) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Acetone SCHEMBL27616570 | 0.90 | CYP2C19 (0.38) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Benzene SCHEMBL27454874 | 0.89 | CYP3A4 (0.40) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| Benzene SCHEMBL27613941 | 0.89 | CA1 (0.41) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| SCHEMBL29555130 | 0.89 | TSHR (0.43) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 | |
| SCHEMBL29376031 | 0.89 | TSHR (0.43) | CYP2C19CYP3A4TSHRCYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923765-A | Detergent Composition For Process Of Manufacturing Semiconductors And Displays | COWON INNOTECH INC | 2014-07-16 | — | — | CN | claimed |
| CN-103923765-A | Detergent Composition For Process Of Manufacturing Semiconductors And Displays | COWON INNOTECH INC | 2014-07-16 | — | — | CN | disclosed |
| CN-103827740-A | Method for producing liquid crystal alignment film, liquid crystal alignment film, and liquid crystal display element | NISSAN CHEMICAL IND LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-103289711-A | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display device | JSR CORP | 2013-09-11 | — | — | CN | disclosed |
| CN-103180294-A | Diamine, polyimide precursor, polyimide, liquid-crystal alignment material, liquid-crystal alignment film, and liquid-crystal display element | NISSAN CHEMICAL IND LTD | 2013-06-26 | — | — | CN | disclosed |
| CN-103154808-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same | NISSAN CHEMICAL IND LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103097946-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element using same | NISSAN CHEMICAL IND LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-103068919-A | Heat-stable halogen-free flame retardant copolyester thermoplastic elastomer composition | DU PONT | 2013-04-24 | — | — | CN | disclosed |
| CN-101755003-B | Rubber composition | YOKOHAMA RUBBER CO LTD | 2013-03-06 | — | — | CN | disclosed |
| CN-102654673-A | Manufacturing method for liquid crystal display element, liquid crystal display element and polymer composition | JSR CORP | 2012-09-05 | — | — | CN | disclosed |
| CN-1697738-A | Tire wheel assembly for run-flat tire | YOKOHAMA RUBBER CO LTD (JP) | 2005-11-16 | — | — | CN | disclosed |
| CN-1509304-A | System made from polyamide and 2,6-diaminopyridine derivative and method for producing of the system | �����ɷ� | 2004-06-30 | — | — | CN | disclosed |
| CN-1085705-C | Flame retardant polycarbonate/graft blends exhibiting heat aging stability | GEN ELECTRIC (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1325422-A | Flame retardant resin compositions containing phosphoramides, and method for making same | GEN ELECTRIC (US) | 2001-12-05 | — | — | CN | disclosed |
| CN-1307616-A | Mixed polymer composition comprising crystallizable polyester polymer composition and aromatic polycarbonate, and foamable composition and closed cell polymer foam made therefrom | M & G POLYMER ITALIA S P A (IT) | 2001-08-08 | — | — | CN | disclosed |
| CN-1046894-C | Laminated transparent plastic material and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1999-12-01 | — | — | CN | disclosed |
| CN-1158342-A | Flame retardant polycarbonate/graft blends exhibiting heat aging stability | GEN ELECTRIC (US) | 1997-09-03 | — | — | CN | disclosed |
| CN-1127762-A | Process thermoplastic compositions and emulsion graft copolymer utilizing a polyacid | GEN ELECTRIC (US) | 1996-07-31 | — | — | CN | disclosed |
| CN-1077448-A | Carboxylicesters as the hydroxyphenylalkanolas of stablizer | CIBA GEIGY AG (CH) | 1993-10-20 | — | — | CN | disclosed |
| CN-1075151-A | Laminated transparent plastic material and polymerisable monomer | MITSUI TOATSU CHEMICALS (JP) | 1993-08-11 | — | — | CN | disclosed |