Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406967 | 0.89 | MAPT (0.41) | ALDH1A1RECQLMTNR1AMTNR1BKMT2A | |
| SCHEMBL27385195 | 0.85 | MAPT (0.41) | ALDH1A1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL27406262 | 0.84 | ALDH1A1 (0.39) | ALDH1A1RECQLKMT2ASMN1; SMN2POLB | |
| SCHEMBL27385594 | 0.84 | SLC13A5 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9594918 | 0.82 | ALDH1A1 (0.40) | ALDH1A1RECQLKMT2AMEN1POLB | |
| SCHEMBL27461092 | 0.81 | ELANE (0.43) | ALDH1A1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL27405551 | 0.80 | KDM4E (0.39) | ALDH1A1RECQLMTNR1AMTNR1BKMT2A | |
| SCHEMBL27407410 | 0.78 | ALDH1A1 (0.42) | ALDH1A1RECQLMTNR1AMTNR1BKMT2A | |
| SCHEMBL27387788 | 0.75 | ELANE (0.46) | ALDH1A1MTNR1AMTNR1BKMT2ASMN1; SMN2 | |
| Bicarbonate SCHEMBL1976713 | 0.75 | CA1 (0.54) | ALDH1A1RECQLKMT2ANOTUMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075060-C | Alkoxy-alkyl-substd. 1-H-3-aryl-pyrrolidine-2,4-diones used as herbicides and pesticides | BAYER AG (DE) | 2001-11-21 | — | — | CN | disclosed |
| CN-1147249-A | Alkoxy-alkyl-substituted 1-H-3-aryl-pyrrolidine-2, 4-diones as herbicides and pesticides | BAYER AG (DE) | 1997-04-09 | — | — | CN | disclosed |