SCHEMBL27403259

SCHEMBL27403259

Cc1c(C(C)C)nc(Cl)n1C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27403257 0.79 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL11985921 0.75
SCHEMBL12775549 0.74 KMT2A (0.37)
SCHEMBL22428055 0.73
SCHEMBL26385522 0.70 ALDH1A1 (0.39) SMN1; SMN2
SCHEMBL10148293 0.68 HTT (0.30)
SCHEMBL12354219 0.66 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL14046050 0.64 ALDH1A1 (0.37)
SCHEMBL24759398 0.63 KDM4E (0.35)
SCHEMBL22017084 0.62 KMT2A (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115512-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-06 WO disclosed