Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895221 | 0.81 | HSD17B10 (0.55) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL27566802 | 0.77 | ALDH1A1 (0.56) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8894861 | 0.74 | MEN1 (0.54) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8896650 | 0.74 | ALDH1A1 (0.63) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL2379547 | 0.74 | ALDH1A1 (0.56) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL7363044 | 0.71 | ALDH1A1 (0.59) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16644714 | 0.71 | MEN1 (0.50) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL14993071 | 0.70 | HSD17B10 (0.52) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8897844 | 0.70 | MEN1 (0.49) | HSD17B10MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8896465 | 0.70 | HSD17B10 (0.51) | HSD17B10MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107158-A | Polysubstituted 2-amino-thiazole derivatives | SANOFI ELF (FR) | 1995-08-23 | — | — | CN | disclosed |