Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 17/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.64 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 3/20 | 0.51 |
| ▸ | IL1B | P01584 | 3/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27404411 | 0.96 | CRBN (0.63) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL27404528 | 0.95 | CRBN (0.62) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL27404574 | 0.94 | CRBN (0.61) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL27404250 | 0.90 | CRBN (0.66) | CRBNIKZF3DDB1TNFIL1B | |
| SCHEMBL30890233 | 0.89 | CRBN (0.68) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL27404424 | 0.86 | CRBN (0.66) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL25036778 | 0.86 | CRBN (0.51) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL27404546 | 0.85 | CRBN (0.65) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL30890283 | 0.85 | CRBN (0.65) | CRBNIKZF3DDB1MAP1LC3BTNF | |
| SCHEMBL30936956 | 0.84 | CRBN (0.56) | CRBNIKZF3DDB1MAP1LC3BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |