Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 10/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.48 |
| ▸ | TNF | P01375 | 3/20 | 0.48 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25036780 | 0.88 | CRBN (0.57) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL19585396 | 0.87 | CRBN (0.54) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL21069970 | 0.87 | STAT3 (0.54) | CRBNMAP1LC3BTNFDDB1 | |
| SCHEMBL27404347 | 0.86 | CRBN (0.64) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL20819237 | 0.86 | CRBN (0.59) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL30936956 | 0.85 | CRBN (0.56) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL30772535 | 0.84 | CRBN (0.55) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL19453154 | 0.84 | CRBN (0.58) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL25182424 | 0.84 | STAT3 (0.54) | CRBNMAP1LC3BIKZF3TNFIKZF1 | |
| SCHEMBL29091122 | 0.84 | CRBN (0.54) | CRBNMAP1LC3BBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |