Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850637 | 0.96 | HTR6 (0.52) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL28198594 | 0.92 | HTR6 (0.52) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL164409 | 0.87 | HTR6 (0.70) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL197508 | 0.87 | HTR6 (0.78) | HTR6CA12CA1CA2CA9 | |
| (Phenylsulfonyl)Benzene SCHEMBL28196220 | 0.84 | HTR6 (0.74) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL3026340 | 0.84 | HTR6 (0.74) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL9001233 | 0.82 | HTR6 (0.68) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL18194389 | 0.82 | HTR6 (0.68) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL28722110 | 0.82 | GAA (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27401824 | 0.81 | HTR6 (0.50) | HTR6CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1104413-C | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 2003-04-02 | — | — | CN | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |