Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.41 |
| ▸ | USP2 | O75604 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12074845 | 0.91 | NOTUM (0.50) | NOTUMCYP3A4USP2CYP2C19CYP1A2 | |
| SCHEMBL27408091 | 0.86 | CYP3A4 (0.38) | NOTUMCYP3A4USP2CYP2C19CYP1A2 | |
| SCHEMBL27405151 | 0.81 | NOTUM (0.46) | NOTUMCYP3A4ALDH1A1TSHRHRH3 | |
| SCHEMBL27405104 | 0.81 | NOTUM (0.49) | NOTUMCYP3A4USP2CYP2C19CYP1A2 | |
| SCHEMBL3534359 | 0.81 | NOTUM (0.54) | NOTUMALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL14349225 | 0.81 | NOTUM (0.54) | NOTUMALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL16775753 | 0.79 | NOTUM (0.45) | NOTUMCYP3A4USP2CYP2C19CYP1A2 | |
| SCHEMBL4547919 | 0.79 | NOTUM (0.52) | NOTUMUSP2ALDH1A1HSD17B10TSHR | |
| SCHEMBL12074842 | 0.79 | NOTUM (0.47) | NOTUMCYP3A4USP2CYP2C19CYP1A2 | |
| SCHEMBL16019525 | 0.77 | NOTUM (0.56) | NOTUMALDH1A1TSHRHRH3ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | NOTUM 3091/4885CYP3A4 2981/4885USP2 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.