Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351731 | 0.85 | NQO2 (0.49) | NAMPTNQO2CYP3A4CYP2C19IDO1 | |
| SCHEMBL732230 | 0.83 | NQO2 (0.50) | NAMPTNQO2IDO1POLBKDM4E | |
| SCHEMBL6675643 | 0.81 | CYP3A4 (0.49) | NAMPTNQO2CYP3A4CYP2C19IDO1 | |
| SCHEMBL3068695 | 0.81 | CYP3A4 (0.52) | NAMPTNQO2CYP3A4CYP2C19IDO1 | |
| SCHEMBL31505839 | 0.80 | NQO2 (0.62) | NAMPTNQO2IDO1POLBKDM4E | |
| SCHEMBL9985225 | 0.80 | NQO2 (0.52) | NAMPTNQO2CYP3A4CYP2C19IDO1 | |
| SCHEMBL16787407 | 0.80 | POLB (0.62) | NAMPTNQO2IDO1POLBKDM4E | |
| SCHEMBL69058 | 0.80 | NQO2 (0.62) | NAMPTNQO2IDO1POLBKDM4E | |
| SCHEMBL6676208 | 0.80 | CA2 (0.49) | NAMPTNQO2CYP3A4CYP2C19IDO1 | |
| SCHEMBL25046691 | 0.80 | NQO2 (0.45) | NAMPTNQO2CYP3A4CYP2C19IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075808-C | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2001-12-05 | — | — | CN | disclosed |