Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28110796 | 0.93 | TAAR1 (0.67) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28196228 | 0.93 | TAAR1 (0.67) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27415476 | 0.91 | MEN1 (0.59) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL23049451 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19139417 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19417186 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30239367 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8487288 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19417180 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15684031 | 0.88 | MEN1 (0.71) | TAAR1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087015-C | Pyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-07-03 | — | — | CN | disclosed |
| CN-1169721-A | Pyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-01-07 | — | — | CN | disclosed |