Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27408485 | 0.91 | TAAR1 (0.58) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28110796 | 0.91 | TAAR1 (0.67) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28196228 | 0.91 | TAAR1 (0.67) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL15684033 | 0.89 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL14389682 | 0.87 | MEN1 (0.70) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL16871023 | 0.84 | MEN1 (0.70) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8480067 | 0.83 | MEN1 (0.69) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28135501 | 0.83 | TAAR1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL27416185 | 0.81 | CTRC (0.54) | TAAR1 | |
| SCHEMBL3787922 | 0.80 | TAAR1 (0.64) | MEN1TAAR1MAOACYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087015-C | Pyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-07-03 | — | — | CN | disclosed |
| CN-1169721-A | Pyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-01-07 | — | — | CN | disclosed |