SCHEMBL27409336

SCHEMBL27409336

C#CCN(C(N)=O)C(=O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27567314 0.74
SCHEMBL28273864 0.70
SCHEMBL27275978 0.70 ALOX15 (0.35)
SCHEMBL27498597 0.68 ALOX15 (0.33)
SCHEMBL27739478 0.68 TDP1 (0.35)
SCHEMBL28055075 0.68
Hydrogen Sulfide SCHEMBL28769767 0.68 ALOX15 (0.33)
Hydrochloric Acid SCHEMBL27352987 0.67 SLC6A2 (0.30)
SCHEMBL8306547 0.67
SCHEMBL27618935 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1243738-C Method for preparing 1-proparagyl hydantoin KAIDA FINE CHEMICAL INDUSTRY C (CN) 2006-03-01 CN claimed
CN-1129942-A Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity ISRAEL INST BIOLOG RES (IL) 1996-08-28 CN claimed
CN-1129942-B Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity ISRAEL INST BIOLOG RES 2011-08-10 CN disclosed
CN-101845020-A Fluorinated pyrethroid compound and application thereof DALIAN HETEROGENEOUS CATALYST CO LTD 2010-09-29 CN disclosed
CN-1243738-C Method for preparing 1-proparagyl hydantoin KAIDA FINE CHEMICAL INDUSTRY C (CN) 2006-03-01 CN disclosed
CN-1103761-C Process for producing 1 -substituted -hydantoins SUMITOMO CHEMICAL CO (JP) 2003-03-26 CN disclosed
CN-1172804-A Process for producing 1 -substituted -hydantoins SUMITOMO CHEMICAL CO (JP) 1998-02-11 CN disclosed
CN-1129942-A Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity ISRAEL INST BIOLOG RES (IL) 1996-08-28 CN disclosed