⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776256 | 0.73 | — | — | |
| SCHEMBL26064958 | 0.69 | — | — | |
| SCHEMBL18653223 | 0.67 | — | — | |
| SCHEMBL9299484 | 0.67 | — | — | |
| SCHEMBL24920800 | 0.67 | — | — | |
| SCHEMBL1361077 | 0.65 | — | — | |
| SCHEMBL5210963 | 0.65 | — | — | |
| SCHEMBL178564 | 0.65 | — | — | |
| SCHEMBL25480019 | 0.65 | — | — | |
| SCHEMBL19934665 | 0.65 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105197-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | VINCERX PHARMA GMBH (DE) | 2024-05-23 | — | — | WO | disclosed |