⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133064 | 0.89 | — | — | |
| SCHEMBL11144733 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL19411337 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL272453 | 0.86 | — | — | |
| SCHEMBL8973807 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL19411336 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL4139743 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL6606689 | 0.86 | — | — | |
| SCHEMBL5599721 | 0.79 | — | — | |
| SCHEMBL2866023 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222290-B1 | ALPHA-AMINOAMIDE DERIVATIVES FOR THE TREATMENT OF PSYCHIATRIC DISORDERS | NEWRON PHARM SPA (IT) | 2021-06-16 | — | — | EP | claimed |
| US-20200071326-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS INC (US) | 2020-03-05 | — | — | US | claimed |
| WO-2018191587-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| CN-104961666-B | 2-mercaptoacetamide pleuromutilin derivatives, and preparation method and medical application thereof | 南通大学 | 2017-04-12 | — | — | CN | claimed |
| CN-105967609-A | Heat-preservation material | 张翔 | 2016-09-28 | — | — | CN | claimed |
| CN-104447450-B | Cysteine amide-type pleuromutilin derivative and preparation method and medical usage | 南通大学 | 2016-09-28 | — | — | CN | claimed |
| CN-104961666-A | 2-mercaptoacetamide pleuromutilin derivatives, and preparation method and medical application thereof | UNIV NANTONG | 2015-10-07 | — | — | CN | claimed |
| CN-103193695-B | 3-phenyl-3-pyrryl pentane analog derivative and medicinal use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-104447450-A | Cysteine amide type pleuromutilin derivative as well as preparation method and medical application thereof | UNIV NANTONG | 2015-03-25 | — | — | CN | claimed |
| CN-103193695-A | 3-phenyl-3-pyrrolyl pentane derivative and medical application thereof | UNIV CHINA PHARMA | 2013-07-10 | — | — | CN | claimed |
| US-20050165229-A1 | Novel process | PFIZER, INC. (US) | 2005-07-28 | — | — | US | claimed |
| US-20020058806-A1 | Novel process | ZOETIS SERVICES LLC | 2002-05-16 | — | — | US | claimed |
| EP-1178049-A1 | Process for the preparation of cephalosporin compounds and intermediates for the synthesis of these compounds | PFIZER INC. (US) | 2002-02-06 | — | — | EP | claimed |
| EP-0763015-A1 | SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE- BASED MOLECULES HAVING AT LEAST TWO STRUCTURAL DIVERSITY ELEMENTS | ARQULE, INC. (US) | 1997-03-19 | — | — | EP | claimed |
| WO-1995032184-A1 | SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE- BASED MOLECULES HAVING AT LEAST TWO STRUCTURAL DIVERSITY ELEMENTS | ARQULE, INC. (US) | 1995-11-30 | — | — | WO | claimed |
| EP-0594790-A4 | POLYACRYLAMIDE GEL MATRIX. | NAT DIAGNOSTICS (US) | 1994-11-09 | — | — | EP | claimed |
| EP-0594790-A1 | POLYACRYLAMIDE GEL MATRIX | NATIONAL DIAGNOSTICS (US) | 1994-05-04 | — | — | EP | claimed |
| WO-1993002115-A1 | POLYACRYLAMIDE GEL MATRIX | NATIONAL DIAGNOSTICS (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0112517-B1 | POLYETHER COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-04-16 | — | — | EP | claimed |
| EP-0112517-A1 | Polyether compounds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-07-04 | — | — | EP | claimed |