SCHEMBL27410012

SCHEMBL27410012

O=C1CSC(c2ccccc2)N1CCC(O)(C(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
LMNA P02545 6/20 0.49
HPGD P15428 4/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ALOX12 P18054 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 2/20 0.46
CACNA1B Q00975 1/20 0.46
GAA P10253 2/20 0.46
HTT P42858 1/20 0.46
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27391713 0.92 CYP2C9 (0.48) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL27480003 0.91 POLB (0.48) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL8444032 0.83 PTGS1 (0.65) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL8635567 0.77 PTGS1 (0.55) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL7204874 0.77 CYP2C9 (0.56) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL27389982 0.76 CYP2C9 (0.53) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL13501913 0.75 MEN1 (0.56) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL3549503 0.75 CYP2C9 (0.61) CYP2C9CYP2C19LMNAHPGDMEN1
SCHEMBL8633070 0.75 PTGS1 (0.52) MEN1KMT2APTGS1PTGS2NPSR1
SCHEMBL2101055 0.74 PTGS1 (0.55) LMNAHPGDMEN1KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1091741-A Tartronic acid and acetal ether thereof and O-ester DOMPE FARMACEUTICI SPA (IT) 1994-09-07 CN disclosed