Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635567 | 0.90 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL5417232 | 0.88 | LMNA (0.68) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL8633070 | 0.88 | PTGS1 (0.52) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL2101055 | 0.86 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL8635508 | 0.86 | MEN1 (0.54) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL7204874 | 0.83 | CYP2C9 (0.56) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL27389982 | 0.83 | CYP2C9 (0.53) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL27410012 | 0.83 | CYP2C9 (0.50) | PTGS1PTGS2MEN1KMT2ACYP2C9 | |
| SCHEMBL3549503 | 0.81 | CYP2C9 (0.61) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL13501913 | 0.81 | MEN1 (0.56) | PTGS1PTGS2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998452-A | CARDIOVASCULAR DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-12-07 | — | — | US | claimed |