Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410163 | 0.98 | MEN1 (0.40) | MEN1KMT2AAPPPTGS1PTGS2 | |
| SCHEMBL27410068 | 0.95 | MEN1 (0.37) | MEN1KMT2AAPPPTGS1PTGS2 | |
| SCHEMBL27410311 | 0.85 | APP (0.42) | MEN1KMT2AAPPPTGS1PTGS2 | |
| SCHEMBL26481790 | 0.82 | CYP3A4 (0.35) | KMT2AAPPPTGS1PTGS2SLC5A2 | |
| SCHEMBL26565787 | 0.80 | CTSK (0.35) | CTSKCTSCTSHR | |
| SCHEMBL26481787 | 0.80 | CTSK (0.34) | APPPTGS1PTGS2SLC5A2CTSK | |
| SCHEMBL26481784 | 0.79 | CTSK (0.35) | SLC5A2CTSKCTSC | |
| SCHEMBL26481792 | 0.78 | CTSK (0.35) | CTSKCTSC | |
| SCHEMBL26481791 | 0.77 | CTSK (0.35) | FFAR4SLC5A2CTSKCTSC | |
| SCHEMBL224331 | 0.77 | GRIN2B (0.34) | MEN1KMT2APTGS2CTSKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126567-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |