SCHEMBL274103

SCHEMBL274103

CCN(CC)CCNCc1ccc(C(=O)Nc2ccc(Br)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC34A2 O95436 9/20 0.42
GCGR P47871 1/20 0.36
HDAC1 Q13547 1/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
NPC1 O15118 2/20 0.35
ALDH1A1 P00352 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
PLEC Q15149 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
F10 P00742 1/20 0.35
ADCYAP1R1 P41586 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PKM P14618 1/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269029 1.00 SLC34A2 (0.42) SLC34A2GCGRHDAC1MAPTKDM4E
SCHEMBL269030 1.00 SLC34A2 (0.42) SLC34A2GCGRHDAC1MAPTKDM4E
SCHEMBL273585 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTNPC1
SCHEMBL268397 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTNPC1
SCHEMBL268396 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTNPC1
SCHEMBL274240 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTKDM4E
SCHEMBL273425 0.89 SLC34A2 (0.49) SLC34A2KDM4EALDH1A1F10
SCHEMBL266788 0.89 SLC34A2 (0.49) SLC34A2KDM4EALDH1A1F10
SCHEMBL268070 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTKDM4E
SCHEMBL268071 0.89 SLC34A2 (0.38) SLC34A2GCGRHDAC1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-05-10 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME SLC34A1, SLC34A2, SLC20A2 SLC34A2 2/4885GCGR 797/4885HDAC1 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.