SLC20A2

Sodium-dependent phosphate transporter 2 · Q08357 · SLC20A2 on Sugi Atlas →

499 patent compounds predicted against SLC20A2, 370 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL7128814 SCHEMBL7128814 1.00 1/20
SCHEMBL7631719 SCHEMBL7631719 0.86 1/20
SCHEMBL7126685 SCHEMBL7126685 0.83 1/20
SCHEMBL7120286 SCHEMBL7120286 0.74 1/20
SCHEMBL12201483 SCHEMBL12201483 0.72 1/20
SCHEMBL6380677 SCHEMBL6380677 0.71 1/20
SCHEMBL7208743 SCHEMBL7208743 0.70 1/20
SCHEMBL5110940 SCHEMBL5110940 0.66 1/20
SCHEMBL6862230 SCHEMBL6862230 0.66 1/20
SCHEMBL5115424 SCHEMBL5115424 0.66 1/20
SCHEMBL7128725 SCHEMBL7128725 0.66 1/20
SCHEMBL7530790 SCHEMBL7530790 0.65 1/20
SCHEMBL7578393 SCHEMBL7578393 0.64 1/20
SCHEMBL7572438 SCHEMBL7572438 0.63 1/20
SCHEMBL27179805 SCHEMBL27179805 0.63 1/20
SCHEMBL30927042 SCHEMBL30927042 0.63 1/20
SCHEMBL5120085 SCHEMBL5120085 0.63 1/20
SCHEMBL23200355 SCHEMBL23200355 0.63 1/20
SCHEMBL30926890 SCHEMBL30926890 0.63 1/20
SCHEMBL7209341 SCHEMBL7209341 0.62 1/20

Clinical trials — most relevant to SLC20A2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation. PHASE4COMPLETED
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH PHASE3COMPLETED
Study to Evaluate the Efficacy and Safety of PT20 in Subjects With Hyperphosphataemia and Dialysis Dependent Chronic Kidney Disease PHASE2COMPLETED
A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP) PHASE2COMPLETED
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia PHASE1/PHASE2COMPLETED
Evaluating Safe Ketone Thresholds To Minimise Ketosis in People With Type 1 Diabetes Using Dapagliflozin PHASE2NOT_YET_RECRUITING
Healthy Combine Study PHASE1COMPLETED
PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias PHASE1COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters EARLY_PHASE1COMPLETED
Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I EARLY_PHASE1COMPLETED
Cardiovascular Effects of Empagliflozine nanUNKNOWN
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
The Effectiveness and Safety of Calcium Carbonate in Chronic Kidney Disease With Normophosphatemia nanCOMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study nanCOMPLETED
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Calcitonin for Treating X-linked Hypophosphatemia nanCOMPLETED
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS nanNOT_YET_RECRUITING
Oxalate and Citrate nanRECRUITING
Studying Phosphorus Metabolism nanCOMPLETED
Blood Pressure Control in Juveniles - Longitudinal Study nanCOMPLETED
Epidemiology of Gout in French Polynesia nanCOMPLETED
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management nanUNKNOWN
Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs nanCOMPLETED
Impact of SGLT2 Inhibitors on Chronic Peritoneal Dialysis Patients. nanRECRUITING
Lithium Countertransport and Blood Pressure In CARDIA and TOMHS nanCOMPLETED
Impact of Genetics on Metformin Pharmacokinetics nanCOMPLETED
Impact of Sodium Glucose Co-transporter 2-Inhibitors on Clinical Outcome and Left Ventricular Function in Patients Presented by Acute Myocardial Infarction nanCOMPLETED
Coproporphyrine Isomers and Methotrexate Elimination nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SLC20A2 binder may also engage these)

ProteinNameSimilarity
Q28E01 1.000 Q28E01 →
A1A4I1 1.000 A1A4I1 →
Q5XHF9 1.000 Q5XHF9 →
Q9ES44 1.000 Q9ES44 →
Q95L97 1.000 Q95L97 →
Q80UP8 1.000 Q80UP8 →
Q6PFM1 1.000 Q6PFM1 →
Q5BL44 1.000 Q5BL44 →
Q9JJP0 1.000 Q9JJP0 →
Q61609 1.000 Q61609 →
Q63488 1.000 Q63488 →
O97596 1.000 O97596 →
Q5R9L5 1.000 Q5R9L5 →
SLC20A1 Sodium-dependent phosphate transporter 1 1.000 landscape →
Q6PB26 0.999 Q6PB26 →
Q6NV12 0.997 Q6NV12 →
Q68F35 0.994 Q68F35 →
Q9JIS8 0.986 Q9JIS8 →
Q27960 0.986 Q27960 →
P15710 0.985 P15710 →
Q5REV9 0.983 Q5REV9 →
Q9DBP0 0.983 Q9DBP0 →
Q924N4 0.983 Q924N4 →
Q9UHW9 0.982 Q9UHW9 →
A0JNI9 0.982 A0JNI9 →
Q5DTL9 0.982 Q5DTL9 →
B0JZG0 0.981 B0JZG0 →
Q5Z413 0.981 Q5Z413 →
Q0DWA9 0.981 Q0DWA9 →
S4R2P9 0.981 S4R2P9 →