Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621551 | 0.83 | ACHE (0.43) | ACHEMAPTNPSR1POLBGAA | |
| SCHEMBL12969432 | 0.80 | ACHE (0.44) | ACHEMAPTNPSR1POLBGFER | |
| SCHEMBL12586888 | 0.79 | ACHE (0.54) | ACHEMAPTNPSR1POLBGFER | |
| SCHEMBL10584398 | 0.79 | ACHE (0.48) | ACHEMAPTNPSR1POLBGFER | |
| SCHEMBL8036573 | 0.79 | MAPT (0.48) | ACHEMAPTNPSR1POLBGAA | |
| SCHEMBL14511738 | 0.78 | ACHE (0.43) | ACHEMAPTNPSR1POLBGFER | |
| SCHEMBL3596792 | 0.77 | POLB (0.42) | ACHEMAPTNPSR1POLBGFER | |
| SCHEMBL27408439 | 0.77 | CYP3A4 (0.43) | MAPTNPSR1POLBGFERGAA | |
| Hydrochloric Acid SCHEMBL10426497 | 0.77 | MAPT (0.46) | ACHEMAPTNPSR1POLBGAA | |
| SCHEMBL2845433 | 0.76 | ACHE (0.50) | ACHEMAPTPOLBGFERGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127363-A1 | TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2024-06-20 | — | — | WO | disclosed |