SCHEMBL27411006

SCHEMBL27411006

CC(C)(C)c1c(-c2csc(N3[C@@H]4CCC[C@H]3CC4)n2)ccc(F)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 8/20 0.35
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ CYP1A2 P05177 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27413227 0.89 AR (0.38) ARNPC1RAB9ASMN1; SMN2
SCHEMBL27411002 0.89 AR (0.40) ARNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL27411038 0.88 AR (0.41) ARNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL27411004 0.87 AR (0.33) ARNPC1RAB9ASMN1; SMN2NPSR1
SCHEMBL26503298 0.82 AR (0.47) ARNPC1RAB9ASMN1; SMN2
SCHEMBL27411008 0.81 AR (0.36) ARSMN1; SMN2TYR
SCHEMBL27413291 0.79 AR (0.40) ARNPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL27413224 0.78 AR (0.43) ARNPC1RAB9ASMN1; SMN2
SCHEMBL26503296 0.77 AR (0.60) ARNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL27413226 0.77 AR (0.36) ARNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 AR 1/4885NPC1 3776/4885RAB9A 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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