Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680475 | 0.83 | HRH4 (0.36) | BDKRB2HRH4 | |
| SCHEMBL27477222 | 0.72 | PDPK1 (0.37) | HRH4PDE10A | |
| SCHEMBL27434416 | 0.72 | CYP1A2 (0.35) | CRHR1RORC | |
| SCHEMBL27476597 | 0.71 | MAPT (0.42) | RORC | |
| SCHEMBL16583445 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL27413977 | 0.69 | SMN1; SMN2 (0.39) | RORC | |
| SCHEMBL27555336 | 0.69 | NPC1 (0.36) | HRH4RORC | |
| SCHEMBL27476598 | 0.68 | SMN1; SMN2 (0.39) | RORC | |
| SCHEMBL27413424 | 0.67 | NQO2 (0.36) | HRH4 | |
| SCHEMBL27434418 | 0.67 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103770-C | Quinoxalinediones | PFIZER RES AND DEV CO N V S A (IE) | 2003-03-26 | — | — | CN | disclosed |
| CN-1213369-A | Quinoxalinedione compound | PFIZER RES & DEV (IE) | 1999-04-07 | — | — | CN | disclosed |