Tyrosine

Tyrosine

SCHEMBL27411908

NC(Cc1ccc(O)cc1)C(=O)O.O=[N+]([O-])c1cccc([N+](=O)[O-])c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.65
KMO O15229 1/20 0.56
GRM8 O00222 5/20 0.52
GRM4 Q14833 5/20 0.52
GRM6 O15303 4/20 0.52
PTGS1 P23219 2/20 0.51
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
XIAP P98170 1/20 0.51
GRIA2 P42262 1/20 0.50
MMP2 P08253 1/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
EGFR P00533 1/20 0.49
LCK P06239 1/20 0.49
FYN P06241 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
ALOX15 P16050 1/20 0.49
HTR2A P28223 1/20 0.49
PTGS2 P35354 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL27497255 0.92 SLC7A5 (0.69) SLC7A5KMOPTGS1ALPIPKM
Dl-Phenylalanine SCHEMBL27765394 0.90 ALPI (0.65) SLC7A5KMOGRM8GRM4GRM6
Tyrosine SCHEMBL8933182 0.89 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27459414 0.89 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL29616010 0.86 GRM8 (0.63) SLC7A5KMOGRM8GRM4GRM6
SCHEMBL44004 0.86 GRM8 (0.63) SLC7A5KMOGRM8GRM4GRM6
SCHEMBL30232038 0.86 GRM8 (0.63) SLC7A5KMOGRM8GRM4GRM6
SCHEMBL44005 0.86 GRM8 (0.63) SLC7A5KMOGRM8GRM4GRM6
SCHEMBL8083539 0.86 GRM8 (0.63) SLC7A5KMOGRM8GRM4GRM6
Hydrochloric Acid SCHEMBL8127068 0.85 GRM8 (0.62) SLC7A5KMOGRM8GRM4GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101801995-A Antibacterial peptide AMP THERAPEUTICS GMBH & CO KG 2010-08-11 CN claimed
CN-101443351-A Modified hematopoiesis-promoting molecules APLAGEN GMBH (DE) 2009-05-27 CN claimed
CN-101801995-B Antibacterial peptide AMP THERAPEUTICS GMBH & CO KG 2013-10-30 CN disclosed
CN-102369210-A Antibacterial peptide AMP THERAPEUTICS GMBH & CO KG 2012-03-07 CN disclosed
CN-101801995-A Antibacterial peptide AMP THERAPEUTICS GMBH & CO KG 2010-08-11 CN disclosed
CN-101443351-A Modified hematopoiesis-promoting molecules APLAGEN GMBH (DE) 2009-05-27 CN disclosed
CN-101184769-A Diagnostic and therapeutic agents KARYON CTT LTD (FI) 2008-05-21 CN disclosed
CN-1100777-C N-heterocyclic derivatives as NOS inhibitor BERLEX LAB (US) 2003-02-05 CN disclosed
CN-1252799-A N-heterocyclic derivatives as NOS inhibitor BERLEX LAB (US) 2000-05-10 CN disclosed